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罗剑

 

 
罗剑 教授 博导 
教育部"长江学者"青年学者(已公示)
 
华东师范大学 生命科学学院 生命医学研究所 
上海市调控生物学重点实验室
 
地址: 上海市东川路500号 华东师范大学闵行校区生命科学学院531室
办公室: 021-24206947
实验室: 021-24206704
传真: 021-54344922
电子邮箱: jluo@bio.ecnu.edu.cn
 
Jian Luo Ph.D. & Professor
 
Young Scholar of the Yangtze River Scholars Program by Ministry of Education of China
Professor of Biochemistry and Molecular Biology 
Shanghai Key Laboratory of Regulatory Biology
The Institute of Biomedical Sciences
School of Life Sciences
East China Normal University
 
500 Dongchuan Road
Shanghai China, 200241 
Office: +86-21-2420-6947
Lab: +86-21-2420-6704
Fax: +86-21-5434-4922
Email: jluo@bio.ecnu.edu.cn
 
教育和工作经历 Education and Professional Expericence
 
2007年 美国Texas A&M Health Science Center和湖南师范大学,博士
2009年至2014年 华东师范大学生命科学学院,副教授
2014年至今 华东师范大学生命科学学院,教授
2012年至今 第二军医大学附属上海长征医院 华东师范大学-上海长征医院骨肿瘤联合研究中心,副主任,兼职教授
2015年至今 上海交大附属上海第六人民医院南院 华东师范大学-奉贤中心医院转化医学联合研究中心,兼职教授
 
2002-2007 Texas A&M Health Science Center and Hunan Normal University, Ph.D.
2009-2014 East China Normal University, Associate Professor
2014-present East China Normal University, Professor
2012-present East China Normal University and Shanghai Changzheng Hospital Joint Research Center for Orthopedic Oncology, The Second Military Medical University Affiliated Shanghai Changzheng Hospital, Adjunct Professor
2015-present East China Normal University and Shanghai Fengxian District Central Hospital Joint Center for Translational Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus, Adjunct Professor
 
 
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课题组招聘信息:
 
本课题组一直从事骨骼和肿瘤生物学基础及转化医学研究,致力于骨科疾病包括骨肿瘤、骨质疏松和关节炎等分子病理学研究和骨科疾病实验动物模型的建立,已取得多项国际领先的科研成果。并且与第二军医大学附属上海长征医院强强联合,共同组建华东师范大学-上海长征医院骨肿瘤联合研究中心;与上海交通大学第六人民医院南院共同组建华东师范大学-上海市奉贤区中心医院转化医学联合研究中心。根据学科发展的需要,课题组招聘优秀副研究员助理研究员博士后,欢迎有志同仁申请。
 
个人待遇:
副研究员 年薪20-30万元,并享受重点实验室及学校其他相关福利和人才政策。
助理研究员 年薪10-20万元,并享受重点实验室及学校其他相关福利和人才政策。
博士后 年薪25-30万元,并享受联合研究中心及相关医院的相关福利和人才政策。
 
1、副研究员有高校事业单位编制;
2、副研究员推荐申请学校“紫江青年学者”人才计划;此外根据工作职责和业绩按学校规定核发岗位津贴和绩效奖励; 基本工资和地方津贴补贴分别按国家和地方规定的标准执行;
3、学校按校内同类人员标准提供社会保险、职业年金及住房公积金;
4、按学校和联合研究中心相关规定享受周转房、子女入学政策(华东师大附幼、附小、附中等教育资源)及科研等方面的奖励政策;
5、其它待遇按学校及联合研究中心相关人才政策规定办理。
 
任职条件:
1. 在海内外高水平大学或研究机构从事肿瘤生物学或骨科学或造血干细胞微环境等相关专业,并获得博士学位,有小鼠或大鼠工作经验者优先;
2. 在相关领域以第一作者身份发表高水平学术论文;
 
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教学 Teaching
 
本科生:
华东师大菁英班 《发育生物学》(双语授课)
上海交大致远班 《发育生物学》(英文授课)
 
研究生:
华东师大 《细胞信号转导》
 
For undergraduate students:
Developmental Biology (East China Normal University)
Developmental Biology (Shanghai Jiao Tong University)
 
For graduate students:
Cell Signaling Transduction (East China Normal University)
 
科研 Research
 
I. 研究方向 Research Interest
1. 骨科疾病包括骨肿瘤、骨质疏松和关节炎的分子病理学研究
2. 骨科疾病包括骨肿瘤、骨质疏松和关节炎的药物研发
3. 骨髓干细胞的细胞信号调控网络
 
1. Molecular pathology research on orthopedic oncology, osteoporosis, and arthritis 
2. Drug discovery on orthopedic oncology, osteoporosis, and arthritis
3. Bone marrow stem cell 
 
II. 科研项目 Research Grant
主持国家重点研发计划子课题(2016YFC0902102) 2016至2018 
主持国家自然科学基金面上项目(81472048) 2015至2018 
主持国家自然科学基金面上项目(81272911) 2013至2016 
主持国家自然科学基金面上项目(81071437) 2011至2013 
主持国家自然科学基金青年基金(30800653) 2009至2011
主持上海市科委科研计划项目(15140903600) 2015至2017
主持上海市教委科研创新项目重点项目(14ZZ051) 2014至2016
主持华东师范大学科研创新基金(78210017) 2010至2011 
参与国家973计划(2012CB910402) 2012至2016 
参与国家973计划(2010CB529704) 2010至2014
参与国家自然科学基金重点项目(81330059) 2014至2018 
参与国家自然科学基金重点项目(30930055) 2010至2013 
参与教育部"长江学者和创新团队发展计划"(IRT1128) 2012至2014 
参与上海市科委项目(14140901200) 2014至2016  
参与上海市科委项目(12XD1406100) 2012至2014 
参与上海市科委项目(11140903500) 2011至2013 
参与上海市科委项目(09411950500) 2009至2013 
参与上海市科委项目(09PJ1403900) 2009至2011 
参与上海市科委研发公共服务平台(06DZ22923) 2007至2010 
 
III. 专利 Patent
授权中国专利10项 (ZL200910195266.5, ZL201010137554.8, ZL201110059609.2, ZL201110059600.1, ZL201110059622.8, ZL201110326410.1, ZL201210139633.1, ZL201210439033.7, ZL201310717855.1, ZL201310590483.0)
申请中国专利9项 (200910049554.X, 200910197004.2, 201110232784.7, 201210121057.8, 201210439043.0, 201310320606.9, 201310429958.8, 201410131280.X, 201510094956.7)
申请美国专利1项 (60/812,713)
 
IV. 社会兼职 Membership
2009年至今 中国细胞生物学会会员
2012年至今 中国骨质疏松学会会员
2012年至今 国家自然科学基金委函评评委
2010年至今 担任Cancer Res, Mol Oncol, Tumor Biol, Curr Mol Med, J Agric Food Chem等国际学术期刊评审
 
 V. 参编书籍 Books
1. Luo J, Dong A, Tang X. Chapter 4 p41-48, Tumor Dormancy, Quiescence, and Senescence. Springer Press (2014)
2. Luo J, Liu M. Chapter 33 p441-450, Nutrition and Diet in Menopause. Springer Press (Humana) (2013)
3. 罗剑,吴秀山,第7章 p100-112,《心脏发育概论》,科学出版社 (2006)
4. 罗剑,吴秀山,第11章 p279-292,《信号调控与心脏发育》,化学工业出版社 (2006)
5. 罗剑,吴秀山,第6章 p32-36,《心脏发育研究》,湖南科技出版社 (2004)
 
VI. 发表论文 Peer-reviewed Articles
 
5篇代表性论文 5 Representative Peer-reviewed Articles
 
1). Luo J, Yang Z, Ma Y, Yue Z, Lin H, Qu G, Huang J, Dai W, Li C, Zheng C, Xu L, Chen H, Wang J, Li D, Siwko S, Penninger JM, Ning G, Xiao J, Liu M. LGR4 is a receptor for RANKL that negatively regulates osteoclast differentiation and bone resorption. Nat Med. 2016 May;22(5):539-546. (通讯作者)
(News and Views in Nat Med. 2016 May 5;22(5):460-461; Research highlighted in Sci China Life Sci. 2016 59:735-736; BioCentury Innovations. 2016 April 21)
 
2). Tang X, Jin R, Qu G, Wang X, Li Z, Yuan Z, Zhao C, Siwko S, Shi T, Wang P, Xiao J, Liu M, Luo J. GPR116, an adhesion G-Protein coupled receptor, promotes breast cancer metastasis via the Gaq-p63RhoGEF-Rho GTPase pathway. Cancer Res. 2013 Oct 15;73(20):6206-6218. (通讯作者)
 
3). Fang Y, Chen Y, Yu L, Zheng C, Qi Y, Li Z, Yang Z, Zhang Y, Shi T, Luo J, Liu M. Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1. J Natl Cancer Inst. 2013 Jan 2;105(1):47-58. (通讯作者)
 
4). Wu X, Li Z, Yang Z, Zheng C, Jing J, Chen Y, Ye X, Lian X, Qiu W, Yang F, Tang J, Xiao J, Liu M, Luo J. CADPE suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss through inhibition of MAPK/AP-1 and Ca(2+)-NFAT signaling pathways. J Bone Miner Res. 2012 Jun;27(6):1298-1308. (通讯作者)
 
5). Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Höök M, Liu M. Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56. 
 
2017年
 
Chen S, Bai Y, Li Z, Jia K, He B, Qiu WW, Du C, Siwko S, Liu M, Chen H, Luo J. A Betulinic Acid Derivative SH479 Inhibits Collagen-induced Arthritis by Modulating T Cell Differentiation and Cytokine Balance. Biochem Pharmacol. 2017 Feb 15;126:69-78. (通讯作者)
 
Li J, Jing J, Bai Y, Li Z, Xing R, Ma X, Qiu W, Du C, Siwko S, Liu M, Chen H, Luo J. SH479, a Betulinic Acid Derivative, Ameliorates Experimental Autoimmune Encephalomyelitis by Regulating the Th17/Treg Balance. Mol Pharmacol. 2017 (accepted, 通讯作者)
 
Yue Z, Yuan Z, Zeng L, Wang Y, Lai L, Xue X, Qi J, Zheng Y, Fang Y, Yang Z, Shi T, Li D, Stefan S, Luo J, Liu M. LGR4 modulates breast cancer initiation, metastasis, and cancer stem cells. Oncogene. 2017 (under revision, 通讯作者)
 
2016年
 
Luo J, Yang Z, Ma Y, Yue Z, Lin H, Qu G, Huang J, Dai W, Li C, Zheng C, Xu L, Chen H, Wang J, Li D, Siwko S, Penninger JM, Ning G, Xiao J, Liu M. LGR4 is a receptor for RANKL that negatively regulates osteoclast differentiation and bone resorption. Nat Med. 2016 May;22(5):539-546. (通讯作者) 
(News and Views in Nat Med. 2016 May 5;22(5):460-461; Research highlighted in Sci China Life Sci2016 59:735-736; BioCentury Innovations. 2016 April 21)
 
Xu L, Luo J, Jin R, Yang Z, Wan W, Zhang J, Yang X, Li S, Liu M, Xiao J. Bortezomib Inhibits Giant Cell Tumor of Bone through Induction of Cell Apoptosis and Inhibition of osteoclast Recruitment, Giant Cell Formation and Bone Resorption. Mol Cancer Ther. 2016 May;15(5):854-65. (通讯作者)
 
Ma H, Luo J, Sun Z, Xia L, Shi M, Liu M, Chang J, Wu C. 3D printing of biomaterials with mussel-inspired nanostructures for tumor therapy and tissue regeneration. Biomaterials. 2016 Oct 5;111:138-148. (并列第一作者)
(News in Mater Today 2016 Nov. 18) 
 
Wang C, Wang X, Dong K, Luo J, Zhang Q, Cheng Y. Injectable and responsively degradable hydrogel for personalized photothermal therapy. Biomaterials. 2016 Oct;104:129-37.
 
 
2015年
 
Li J, Zeng L, Xie J, Yue Z, Deng H, Ma X, Zheng C, Wu X, Luo J, Liu M. Inhibition of Osteoclastogenesis and Bone Resorption in vitro and in vivo by a prenylflavonoid Xanthohumol from hops. Sci Rep. 2015 Dec 1;5:17605. (通讯作者)
 
Cai X, Luo J, Yang X, Deng H, Zhang J, Li S, Wei H, Yang C, Xu L, Jin R, Li Z, Zhou W, Ding J, Chu J, Jia L, Jia Q, Tan C, Liu M, Xiao J. In vivo selection for spine-derived highly metastatic lung cancer cells is associated with increased migration, inflammation and decreased adhesion. Oncotarget. 2015 Sep 8;6(26):22905-17. (通讯作者)
 
Xu JG, Huang C, Yang Z, Jin M, Fu P, Zhang N, Luo J, Li D, Liu M, Zhou Y, Zhu Y.  Complex Structure of LGR4 and Rspo1: Insights into the Divergent Mechanisms of Ligand Recognition by LGR Receptors. J Biol Chem. 2015 Jan 23;290(4):2455-65.
 
Zheng C, Zhou W, Wang T, You P, Zhao Y, Yang Y, Wang X, Luo J, Chen Y, Liu M, Chen H. A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice. PLoS One. 2015 Jul 24;10(7):e0134051.
 
2014年
 
Zheng C, Fang Y, Tong W, Li G, Wu H, Zhou W, Lin Q, Yang F, Yang Z, Wang P, Peng Y, Pang X, Yi Z, Luo J, Liu M, Chen Y. Synthesis and Biological Evaluation of Novel Tetrahydro-β-carboline Derivatives as Antitumor Growth and Metastasis Agents through Inhibiting the Transforming Growth Factor-β Signaling Pathway. J Med Chem. 2014 Feb 13;57(3):600-12. (通讯作者)
 
Yi T, Weng J, Siwko S, Luo J, Li D, Liu M. Lgr4/Gpr48 Inactivation Leads to Aniridia-Genitourinary Anomalies-Mental Retardation Syndrome Defects. J Biol Chem. 2014 Mar 28;289(13):8767-80.
 
Cui H, Wang Y, Huang H, Yu W, Bai M, Zhang L, Bryan BA, Wang Y, Luo J, Li D, Ma Y, Liu M. GPR126 Regulates Developmental and Pathological Angiogenesis through Modulation of VEGFR2 Signaling. J Biol Chem. Dec 12;289(50):34871-85.
 
Wu J, Yu L, Yang F, Li J, Wang P, Zhou W, Qin L, Li Y, Luo J, Yi Z, Liu M, Chen Y. Optimization of 2-(3-(arylalkyl amino carbonyl) phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives as potent antitumor growth and metastasis agents. Eur J Med Chem. 2014 Jun 10;80:340-51. Epub 2014 Apr 24.
 
Hsia TC, Liu WH, Qiu WW, Luo J, Yin MC. Maslinic acid induces mitochondrial apoptosis and suppresses HIF-1α expression in A549 lung cancer cells under normoxic and hypoxic conditions. Molecules. 2014 Nov 28;19(12):19892-906.
 
2013年
 
Tang X, Jin R, Qu G, Wang X, Li Z, Yuan Z, Zhao C, Siwko S, Shi T, Wang P, Xiao J, Liu M, Luo J. GPR116, an adhesion G-Protein coupled receptor, promotes breast cancer metastasis via the Gaq-p63RhoGEF-Rho GTPase pathway. Cancer Res. 2013 Oct 15;73(20):6206-6218. (通讯作者)
 
Fang Y, Chen Y, Yu L, Zheng C, Qi Y, Li Z, Yang Z, Zhang Y, Shi T, Luo J, Liu M. Inhibition of breast cancer metastases by a novel inhibitor of TGFβ receptor 1. J Natl Cancer Inst. 2013 Jan 2;105(1):47-58. (IF=15.3, 通讯作者)
 
Li L, Zhao D, Wei H, Yao L, Dang Y, Amjad A, Xu J, Liu J, Guo L, Li D, Li Z, Zuo D, Zhang Y, Liu J, Huang S, Jia C, Wang L, Wang Y, Xie Y, Luo J, Zhang B, Luo H, Donehower LA, Moses RE, Xiao J, O'Malley BW, Li X. REGγ deficiency promotes premature aging via the casein kinase 1 pathway. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):11005-10.
 
2012年
 
Wu X, Li Z, Yang Z, Zheng C, Jing J, Chen Y, Ye X, Lian X, Qiu W, Yang F, Tang J, Xiao J, Liu M, Luo J. CADPE suppresses RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss through inhibition of MAPK/AP-1 and Ca(2+)-NFAT signaling pathways. J Bone Miner Res. 2012 Jun;27(6):1298-1308. (通讯作者)
 
Li Z, Xiao J, Wu X, Li W, Yang Z, Xie J, Xu L, Cai X, Lin Z, Guo W, Luo J, Liu M. Plumbagin inhibits breast tumor bone metastasis and osteolysis by modulating the tumor-bone microenvironment. Curr Mol Med. 2012 Sep 1;12(8):967-81. (通讯作者)
 
Xu J, Li Z, Luo J, Yang F, Liu T, Liu M, Qiu WW, Tang J. Synthesis and biological evaluation of heterocyclic ring-fused betulinic Acid derivatives as novel inhibitors of osteoclast differentiation and bone resorption. J Med Chem. 2012 Apr 12;55(7):3122-34. (并列第一作者)
 
Tang X, Wang Y, Li D, Luo J, Liu M. Orphan G protein-coupled receptors (GPCRs): biological functions and potential drug targets. Acta Pharmacol Sin. 2012 Mar;33(3):363-71. (通讯作者)
 
Song Y, Dai F, Zhai D, Dong Y, Zhang J, Lu B, Luo J, Liu M, Yi Z. Usnic acid inhibits breast tumor angiogenesis and growth by suppressing VEGFR2-mediated AKT and ERK1/2 signaling pathways. Angiogenesis. 2012 Sep;15(3):421-32.
 
Xiao N, Li H, Luo J, Wang R, Chen H, Chen J, Wang P. Ubiquitin-Specific Protease 4 (USP4) targets TRAF 2 and TRAF6 for deubiquitination and inhibits TNFa-induced cancer cell migration. Biochem J. 2012 Feb 1;441(3):979-86.
 
2011年
 
Li C, Yang Z, Li Z, Ma Y, Zhang L, Zheng C, Qiu W, Wu X, Wang X, Li H, Tang J, Qian M, Li D, Wang P, Luo J, Liu M. Maslinic acid suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss by regulating RANKL-mediated NF-kappaB and MAPK signaling pathways. J Bone Miner Res. 2011 Mar;26(3):644-56. (通讯作者)
 
Dong A, Fang Y, Zhang L, Xie J, Wu X, Zhang LP, Lian X, Chen Y, Luo J, Liu M. Caffeic acid 3,4-dihydroxy-phenethyl ester (CADPE) induces cancer cell senescence by suppressing Twist expression. J Pharmacol Exp Ther. 2011 Oct;339(1):238-47. (通讯作者)
 
Cho SG, Wang Y, Melissa R, Tan K, Zhang W, Luo J, Li D, Liu M. Haploinsufficiency in the pro-metastasis Kiss1 receptor Gpr54 delays breast tumor initiation, progression and lung metastasis. Cancer Res. 2011 Oct 15;71(20):6535-46. (cover story)
 
Chen G, Yin K, Shi L, Fang Y, Qi Y, Li P, Luo J, He B, Liu M, Shi T. Comparative Analysis of Human Protein-Coding and Noncoding RNAs between Brain and 10 Mixed Cell Lines by RNA-Seq. PLoS One. 2011;6(11):e28318.
 
Chen G, Li R, Shi L, Qi J, Hu P, Luo J, Liu M, Shi T. Revealing the missing expressed genes beyond the human reference genome by RNA-Seq. BMC Genomics. 2011 Dec 2;12(1):590.
 
Jia Y, Jing J, Bai Y, Li Z, Liu L, Luo J, Liu M, Chen H. Amelioration of Experimental Autoimmune Encephalomyelitis by Plumbagin through Down-Regulation of JAK-STAT and NF-κB Signaling Pathways. PLoS One. 2011;6(10):e27006.
 
Kuang L, Wang L, Wang Q, Zhao Q, Du B, Li D, Luo J, Liu M, Hou A, Qian M. Cudratricusxanthone G inhibits human colorectal carcinoma cell invasion by MMP-2 down-regulation through suppressing activator protein-1 activity. Biochem Pharmacol. 2011 May 15;81(10):1192-200.
 
Yu W, Qiu Z, Gao N, Wang L, Cui H, Qian Y, Jiang L, Luo J, Yi Z, Lu H, Li D, Liu M. PAK1IP1, a ribosomal stress-induced nucleolar protein, regulates cell proliferation via the p53-MDM2 loop. Nucleic Acids Res. 2011 Mar 1;39(6):2234-48.
 
2010年
 
Li C, Yang Z, Zhai C, Qiu W, Li D, Yi Z, Wang L, Qian M, Luo J, Liu M. Maslinic acid potentiates the anti-tumor activity of tumor necrosis factor alpha by inhibiting NF-kappaB signaling pathway. Mol Cancer. 2010 Apr 6;9(1):73. (通讯作者)
 
Yang Z, Li C, Wang X, Zai C, Wang L, Yi Z, Liu B, Du B, Wu H, Guo X, Liu M, Li D, Luo J. Dauricine induces apoptosis, inhibits proliferation and invasion through inhibiting NF-kappaB signaling pathway in colon cancer cells. J Cell Physiol. 2010 Oct;225(1):266-75. (通讯作者)
 
Dong Y, Lu B, Zhang X, Zhang J, Lai L, Li D, Wu Y, Song Y, Luo J, Pang X, Yi Z, Liu M. Cucurbitacin E, a Tetracyclic Triterpenes Compound from Chinese Medicine, Inhibits Tumor Angiogenesis through VEGFR2 Mediated Jak2/STAT3 Signaling Pathway. Carcinogenesis. 2010 Dec;31(12):2097-104.
 
Li C, Qiu W, Yang Z, Luo J, Yang F, Liu M, Xie J, Tang J. Stereoselective synthesis of some methyl substituted steroid hormones and their in vitro cytotoxic activity against human gastric cancer cell line MGC-803. Steroids. 2010 Dec;75(12):859-869.
 
Wang J, Jia M, Zhu L, Yuan Z, Li P, Chang C, Luo J, Liu M, Shi T. Systematical detection of significant genes in microarray data by incorporating gene interaction relationship in biological systems. PLoS One. 2010 Oct 29;5(10):e13721.
 
Wang L, Kuang L, Pan X, Liu J, Wang Q, Du B, Li D, Luo J, Liu M, Hou A, Qian M. Isoalvaxanthone inhibits colon cancer cell proliferation, migration and invasion through inactivating Rac1 and AP-1. Int J Cancer. 2010 Sep 1;127(5):1220-9.
 
Yi T, Tan K, Cho SG, Wang Y, Luo J, Zhang W, Li D, Liu M. Regulation of embryonic kidney branching morphogenesis and glomerular development by KISS1 receptor (GPR54) through NFAT2 and SP1 mediated bmp7 expression. J Biol Chem. 2010 Jun 4;285(23):17811-20.
 
翟春燕,刘明耀,罗剑; 小鼠核因子kB受体活化因子配基活性区的克隆、表达及生物活性分析; 生物物理学报 2010 26:225-233. (通讯作者)
 
张立鹏,李成海,刘明耀,罗剑; 构建抑制NF-kB信号通路的药物筛选模型; 激光生物学报 2010 19:580-586. (通讯作者)
 
汪秀,罗剑; G蛋白偶联受体信号通路与癌症的关系研究; 中国医学创新 2010 7:24-25. (通讯作者)
 
2010年以前
 
Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Höök M, Liu M. Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56. (第一作者)
 
Song H, Luo J, Luo W, Weng J, Wang Z, Li B, Li D, and Liu M. Inactivation of G-protein coupled receptor 48 (Gpr48/Lgr4) impairs definitive erythropoiesis at midgestation through downregulation of ATF4 Signaling pathway. J Biol Chem. 2008 Dec 26;283(52):36687-97. (并列第一作者)
 
Li D, Niu Z, Yu W, Qian Y, Wang Q, Li Q, Yi Z, Luo J, Wu X, Wang Y, Schwartz RJ, Liu M. SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin. Nucleic Acids Res. 2009 Nov;37(21):7059-71.
 
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