Nano Medical and Biological Materials Laboratory
Prof. Yiyun Cheng
Shanghai Key Laboratory of Regulatory Biology, School of Life Sciences，East China Normal University
Address: Room 135, School of Life Sciences, East China Normal University, Dongchuan Road 500, Shanghai, P.R. China, 200241.
Tel: +86-021-54341001
Fax: +86-021-54342935
E-mail: yycheng@mail.ustc.edu.cn
Research Interest
1. Design of High efficient and low cytotoxic gene carriers
2. Preparation of dendrimer-based biomaterials for the delivery of anti-cancer therapeutics
3. NMR techniques in the design and optimization of dendrimer-based drug formulations
Education and Work Experience
2010-now: Professor in the School of Life Sciences, East China Normal University;
2009: Postdoctoral research fellow in the Department of Biomedical Engineering, Washington University in St.Louis;
2004-2008: PhD candidate in the School of Life Sciences, University of Science and Technology of China;
2000-2004: Undergraduate student in the Department of Polymer Science and Engineering, University of Science and Technology of China.
Editors and Editorial Board Members
2010-now: Current Drug Discovery Technologies (Regional Editor)
Books
Cheng Yiyun (Editor-in-Chief). “Dendrimer-based Drug Delivery Systems: from Theory to Practice”, John Wiley & Sons, 2012.
Awards
2011: Excellent Talents in the New Century of the Ministry of Education;
2011: Excellent Doctoral Dissertation Award in Anhui Province;
2011: Nomination Award of National Outstanding Doctoral Dissertation;
2010: “Dawn Scholars” in Shanghai (No. 10SG27);
2010: Excellent Doctoral Dissertation Award of CAS (The Chinese Academy of Sciences);
2008: CAS (Chinese Academy of Sciences) President’s Excellent Award;
Selected Publications
1.Yavuz MS†‚ Cheng YY†‚ Chen JY†‚ Cobley CM‚ Zhang Q‚ Rycenga M‚ Xie JW‚ Kim C‚ Schwartz AG‚ Wang LV‚ Xia YN*. Gold Nanocages Covered by Smart Polymers for Controlled Release with Near-infrared Light‚ Nature Materials‚ 2009‚ 8(12): 935-939. (†Co-first authors; Highlighted by Science Daily‚ The New York Times‚ R & D Magazines‚ Nanomedicine)
2.Hu JJ, Xu TW, Cheng YY*. NMR Insights into Dendrimer-based Host-Guest Systems, Chemical Reviews, 2012, 112(7), 3856-3891.
3.Liu HM, Wang H, Yang WJ, Cheng YY*. Disulfide Cross-linked Low Generation Dendrimers with High Gene Transfection Efficacy, Low Cytotoxicity, and Low Cost, Journal of the American Chemical Society‚ 2012‚ 134, 17680-17687. (Highlighted by Global Medical Discovery)
4.Cheng YY*‚ Zhao LB‚ Li YW‚ Xu TW*. Design of Biocompatible Dendrimers for Cancer Diagnosis and Therapy: Current Status and Furture Perspectives‚ Chemical Society Reviews‚ 2011‚ 40‚ 2673-2703.
5.Zhao LB‚ Wu QL‚ Cheng YY*‚ Zhang JH‚ Wu JH‚ Xu TW*. High-throughput Screening of Dendrimer-binding Drugs‚ Journal of the American Chemical Society‚ 2010‚ 132(38)‚ 13182-13184.
6.Hu JJ‚ Su YZ‚ Zhang HF‚ Xu TW‚ Cheng YY*. Design of interior-functionalized fully acetylated dendrimers for anticancer drug delivery‚ Biomaterials‚ 2011‚32(36): 9950-9959.
7.Zhang Q‚ Wang N‚ Xu TW*‚ Cheng YY*. Poly(amidoamine) Dendronized Hollow Fiber Membranes: Synthesis‚ Characterization‚ and Preliminary Applications as Drug Delivery Devices‚ Acta Biomaterialia‚ 2012‚ 8(3)‚ 1316-1322.
8.Wang F, Cai XP, Su YZ, Hu JJ, Wu QL, Zhang HF*, Xiao JR*, Cheng YY*. Reducing the Cytotoxicity while Improving the Anti-cancer Drug Loading Capacity of Polypropylenimine Dendrimers by Surface Acetylation，Acta Biomaterialia, 2012, 8, 4304-4313.
9.Zhang JH, Hu JJ, Feng XY, Li YW, Zhao LB, Xu TW*, Cheng YY*. Interactions between Oppositely Charged Dendrimers. Soft Matter, 2012, 8, 9800-9806.
10.Wang H, Shao NM, Qiao SN, Cheng YY*. Host-guest Chemistry of Dendrimer-Cyclodextrin Conjugates: Selective Encapsulations of Guests within Dendrimer or Cyclodextrin Cavities Revealed by NOE NMR Techniques, Journal of Physical Chemistry B, 2012, 116(36), 11217-11224.