A) 第一作者单位发表论文
1. Fang L, Zhang L, Wei W, Jin X, Wang P, Tong Y, Li J, Du J ,Wong J (2014). A Methylation-Phosphorylation Switch Determines Sox2 Stability and Function in ESC Maintenance or Differentiation. Mol Cell. Aug 21; 55(4):537-51.
2. Wang M, Liu H, Li L, Cheng Y (2014). A Fluorinated Dendrimer Achieves Excellent Gene Transfection Efficiency at Extremely Low Nitrogen to Phosphorus Ratios, Nature Communications 5, 3053.
3. Li P, Liu Y, Wang H, He Y, Wang X, He Y, Lv F, Chen H, Pang X, Liu M, Shi T, Yi Z (2014). "PubAngioGen: a database and knowledge for angiogenesis and related diseases." Nucleic Acids Res.
4. Li S, Jiang C, Pan J, Wang X, Jin J, Zhao L, Pan W, Liao G, Cai X, Li X, Xiao J, Jiang J, Wang P (2014). "Regulation of c-Myc protein stability by proteasome activator REGgamma." Cell Death Differentiation.
5. Ali A, Zhang P, Yao L, Sun W, Wang H, Xiao J, and Li X. KLF17 empowers TGF-β/Smad signaling by targeting Smad3 -dependent pathway to suppress tumor growth and metastasis during cancer progression. Cell Death and Differentiation. In press.
6. Wang F, Wang Y, Wang H, Shao N, Chen Y, Cheng Y (2014). Synergistic Effect of Amino Acids Modified on Dendrimer Surface in Gene Delivery, Biomaterials 35, 9187-9198.
7. Liu H, Wang Y, Wang M, Xiao J, Cheng Y (2014). Fluorinated Poly(propylenimine) Dendrimers as Gene Vectors, Biomaterials 35, 5407-5413.
8. Wang M, Cheng Y (2014). The Effect of Fluorination on the Transfection Efficacy of Surface-Engineered Dendrimers‚ Biomaterials 35, 6603-6613.
9. Pan J, Deng Q, Jiang C, Wang X, Niu T, Li H, Chen T, Jin J, Pan W, Cai X, Yang X, Lu M, Xiao J, Wang P (2014). "USP37 directly deubiquitinates and stabilizes c-Myc in lung cancer." Oncogene.
10. Li C, Li H, Jiang Z, Zhang T, Wang Y, Li Z, Wu Y, Ji S, Xiao S, Ryffel B, Radek K A, Xia Z, Lai Y (2014). "Interleukin-33 increases antibacterial defense by activation of inducible nitric oxide synthase in skin." PLoS Pathog 10(2): e1003918.
11. Shao Y, Guan Y, Wang L, Qiu Z, Liu M, Chen Y, Wu L, Li Y, Ma X, Liu M, Li D (2014). "CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos." Nat Protoc 9(10): 2493-2512.
12. Wang C, Cai X, Zhang J, Xiao J, Zhang Q, Cheng Y (2014). Trifolium-like Platinum Nanoparticle Mediated Photothermal Therapy Inhibits Tumor Growth and Osteolysis in a Bone Metastasis Model, Small smll.201403315, in press.
13. Wang X, Shao N, Zhang Q, Cheng Y(2014) Mitochondrial targeting dendrimer allows efficient and safe gene delivery, J. Mater. Chem. 2, 2546-2553.
14. Lv J, Chang H, Wang Y, Wang M, Xiao J, Zhang Q, Cheng Y (2014). Fluorination on polyethylenimine allows efficient 2D and 3D cell culture gene delivery. J. Mater. Chem. doi: 10.1039/c4tb01447b, in press.
15. Zheng C, Fang Y, Tong W, Li G, Wu H, Zhou W, Lin Q, Yang F, Yang Z, Wang P, Peng Y, Pang X, Yi Z, Luo J, Liu M, Chen Y(2014). Synthesis and Biological Evaluation of Novel Tetrahydro-β-carboline Derivatives as Antitumor Growth and Metastasis Agents through Inhibiting the Transforming Growth Factor-β Signaling Pathway. J Med Chem. 57(3):600-12.
16. Yang F, Zhang T, Wu H, Yang Y, Liu N, Chen A, Li Q, Li J, Qin L, Jiang B, Wang X, Pang X, Yi Z, Liu M, Chen Y (2014). Design and Optimization of Novel Hydroxamate-Based Histone Deacetylase Inhibitors of Bis-Substituted Aromatic Amides Bearing Potent Activities against Tumor Growth and Metastasis. J Med Chem. 2014, 57 (22), 9357-9369.
17. Zhang T, Chen Y, Li J, Yang F, Wu H, Dai F, Hu M, Lu X, Peng Y, Liu M, Zhao Y, Yi Z (2014). Antitumor action of a novel histone deacetylase inhibitor, YF479, in breast cancer. Neoplasia 16(8): 665-677.
18. Li R, Tan B, Yan Y, Ma X, Zhang N, Zhang Z, Liu M, Qian M, Du B (2014). Extracellular UDP and P2Y6 Function as a Danger Signal To Protect Mice from Vesicular Stomatitis Virus Infection through an Increase in IFN-beta Production. J Immunol 193(9): 4515-4526.
19. Liu S, Lai L, Zuo Q, Dai F, Wu L, Wang Y, Zhou Q, Liu J, Liu J, Li L, Lin Q, Creighton C J, Costello M G, Huang S, Jia C, Liao L,Luo H, Fu J, Liu M, Yi Z,Xiao J, Li X (2014). PKA turnover by the REGgamma-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis. J Mol Cell Cardiol 72: 28-38.
20. Liao P, Wang W, Shen M, Pan W, Zhang K, Wang R, Chen T, Chen Y, Chen H, Wang P (2014). A positive feedback loop between EBP2 and c-Myc regulates rDNA transcription, cell proliferation, and tumorigenesis. Cell Death Dis 5: e1032.
21. Chang H, Wang H, Shao N, Wang M, Wang X, Cheng Y(2014). Surface-engineered dendrimers with a diaminododecane core achieve efficient gene transfection and low cytotoxicity. Bioconjugate Chemistry 25, 342-350.
22. Pan H, Cui H, Liu S, Qian Y, Wu H, Li L, Guan Y, Guan X, Zhang L, Fan H Y, Ma Y, Li R, Liu M, Li D (2014). Lgr4 gene regulates corpus luteum maturation through modulation of the WNT-mediated EGFR-ERK signaling pathway. Endocrinology 155(9): 3624-3637.
23. Hu P, Shen Z, Tu H, Zhang L, Shi T (2014). Integrating multiple resources to identify specific transcriptional cooperativity with a Bayesian approach. Bioinformatics 30(6): 823-830.
24. Cui H, Wang Y, Huang H, Yu W, Bai M, Zhang L, Bryan BA, Wang Y, Luo J, Li D, Ma Y, Liu M(2014). GPR126 Regulates Developmental and Pathological Angiogenesis through Modulation of VEGFR2 Signaling. J Biol Chem. Sep 12. [Epub ahead of print]
25. Yi T, Weng J, Siwko S, Luo J, Li D, Liu M(2014). Lgr4/Gpr48 Inactivation Leads to Aniridia-Genitourinary Anomalies-Mental Retardation Syndrome Defects. J Biol Chem. 289(13):8767-80.
26. Zhang Q, Liu X, Gao W, Li P, Hou J, Li J, Wong J (2014). Differential regulation of the ten-eleven translocation (TET) family of dioxygenases by O-linked beta-N-acetylglucosamine transferase (OGT). J Biol Chem 289(9): 5986-5996.
27. Shi G, Wu M, Fang L, Yu F, Cheng S, Li J, Du J ,Wong J (2014). PHD Finger Protein 2 (PHF2) Represses Ribosomal RNA Gene Transcription by Antagonizing PHD Finger Protein 8 (PHF8) and Recruiting Methyltransferase SUV39H1. J Biol Chem. Oct 24; 289(43):29691-700.
28. Chao R, Gong X, Wang L, Wang P, and Wang Y (2014). CD71 population represents primitive erythroblasts derived from mouse embryonic stem cells. Stem Cell Res. 14, 30-38.
29. Wang J, Zhang L, Chen G, Zhang J, Li Z, Lu W, Liu M, Pang X (2014). Small molecule 1'-acetoxychavicol acetate suppresses breast tumor metastasis by regulating the SHP-1/STAT3/MMPs signaling pathway. Breast Cancer Res Treat 148(2): 279-289.
30. Ren H, Teng Y, Tan B, Zhang X, Jiang W, Liu M, Jiang W, Du B, Qian M (2014). Toll-Like Receptor-Triggered Calcium Mobilization Protects Mice against Bacterial Infection through Extracellular ATP Release. Infect Immun 82(12): 5076-5085.
31. Shao N, Dai T, Liu Y, Li L, Cheng Y (2014). Evidence of guest encapsulation within G8 and G10 dendrimers using NMR techniques. Soft Matter 10, 9153-9158.
32. Cheng Y, Zhao L, Li T(2014). Dendrimer-surfactant interactions. Soft Matter 10, 2714-2727.
33. Lv Q, Cheng R, Shi T (2014). Regulatory network rewiring for secondary metabolism in Arabidopsis thaliana under various conditions. BMC Plant Biol 14: 180.
34. Wang B, Yu W, Guo J, Jiang X, Lu W, Liu M, Pang X (2015). The antiparasitic drug, potassium antimony tartrate, inhibits tumor angiogenesis and tumor growth in nonsmall-cell lung cancer. J Pharmacol Exp Ther 352(1): 129-138.
35. Dai F, Chen Y, Huang L, Wang J, Zhang T, Li J, Tong W, Liu M, Yi Z(2014). A novel synthetic small molecule YH-306 suppresses colorectal tumour growth and metastasis via FAK pathway. J Cell Mol Med.
36. Chu M, Wang L, Wang H, Shen T, Yang Y, Sun Y, Tang N, Ni T, Zhu J, Mailman R B, Wang Y (2014). A novel role of CDX1 in embryonic epicardial development. PLoS One 9(7): e103271.
37. Dong Y, Zhang T, Li J, Deng H, Song Y, Zhai D, Peng Y, Lu X, Liu M, Zhao Y, Yi Z (2014). Oridonin Inhibits Tumor Growth and Metastasis through Anti-Angiogenesis by Blocking the Notch Signaling. PLoS One 9(12): e113830.
38. Jiang W, Chen R, Kong X, Long F, Shi Y (2014). Immunization with adenovirus LIGHT-engineered dendritic cells induces potent T cell responses and therapeutic immunity in HBV transgenic mice. Vaccine 32(35): 4565-4570.
39. Wu J, Yu L, Yang F, Li J, Wang P, Zhou W, Qin L, Li Y, Luo J, Yi Z, Liu M,Chen Y (2014). Optimization of 2-(3-(arylalkyl amino carbonyl) phenyl)-3-(2-methoxyphenyl)-4-thiazolidinone derivatives as potent antitumor growth and metastasis agents. Eur J Med Chem 80: 340-351.
40. Qin X, Zheng C, Yates JR 3rd, Liao L (2014). Quantitative phosphoproteomic profiling of PINK1-deficient cells identifies phosphorylation changes in nuclear proteins. Mol Biosyst. 10(7):1719-29.
41. Zhang M, Jiang Z, Li D, Jiang D, Wu Y, Ren H, Peng H, Lai Y (2014). Oral Antibiotic Treatment Induces Skin Microbiota Dysbiosis and Influences Wound Healing. Microb Ecol.
42. Chen A, Qin X, Tang Y, Liu M, Wang X (2014). Evaluation of enzyme inhibition kinetics in drug-drug interactions. Chemico-Biological Interactions 222, 133-134.
43. Chen A, Qin X, Lu J, Yi Z, Liu M, Wang X (2014). Development of a validated LC-MS/MS method for the determination of ailanthone in rat plasma with application to pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis 102, 514-518.
44. Sun M, Tang Y, Ding T, Liu M, Wang X (2014). Investigation of cytochrome P450 inhibitory properties of maslinic acid, a bioactive compound from Olea europaea L., and its structure-activity relationship. Phytomedicine 22, 56-65.
45. Lu J, Qin X, Liu M, Wang X (2014). A note on CYP2J2-mediated terfenadine hydroxylation in human liver microsomes. Food and chemical toxicology 71, 284-285.
46. Ding T, Zhang Y, Chen A, Tang Y, Liu M, Wang X (2014). Effects of Cucurbitacin E, a Tetracyclic Triterpene Compound from Cucurbitaceae, on the Pharmacokinetics and Pharmacodynamics of Warfarin in Rats. Basic & clinical pharmacology & toxicology 2014 Sep 24. doi: 10.1111/bcpt.12329.
47. Wen J, Hao W, Fan Y, Du J, Du B, Qian M, Jiang W (2014). Co-delivery of LIGHT expression plasmid enhances humoral and cellular immune responses to HIV-1 Nef in mice. Arch Virol 159(7): 1663-1669.
48. Chen Y, Wang L, Cheng X, Ge X, Wang P (2014). An ultrasensitive system for measuring the USPs and OTULIN activity using Nanoluc as a reporter. Biochem Biophys Res Commun 455(3-4): 178-183.
49. Sun M, Tang Y, Ding T, Liu M, Wang X (2014). Inhibitory effects of celastrol on rat liver cytochrome P450 1A2, 2C11, 2D6, 2E1 and 3A2 activity. Fitoterapia 92, 1-8.
50. Guan Y, Shao Y, Li D, Liu M (2014). Generation of Site-Specific Mutations in the Rat Genome Via CRISPR/Cas9. Methods Enzymol 546: 297-317.
51. Du B, Liu M (2014). Structure of the human P2Y(1)(2) receptor in complex with an antithrombotic drug. Sci China Life Sci 57(6): 645-646.
52. Wu Y, Li H, Jiang Z, Lai Y (2014). The interleukin-1 family: a key regulator in the pathogenesis of psoriasis. Austin Journal of Clinical Immunology. Accepted.
53. Rodriguez M, Luo W, Weng J, Zeng L, Yi Z, Siwko S, Liu M (2014). PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-kappaB. Oncogenesis 3: e114.
54. Li G, He Y, Zhou W, Wang P, Zhang Y, Tong W, Wu H, Liu M, Ye X, Chen Y (2014). Identification, synthesis and photoprotection evaluation of arylthiazole derivatives as a novel series of sunscreens. Heterocycles. 2014, 89, 453-464.
55. Zhang X, Li B, Li W, Ma L, Zheng D, Li L,Yang W, Chu M, Chen W, Mailman R B, Zhu J, Fan G, Archer T K, Wang Y (2014). Transcriptional repression by the BRG1-SWI/SNF complex affects the pluripotency of human embryonic stem cells. Stem Cell Reports 3(3): 460-474.
B) 合作发表论文：
1. Li L, Wang M, Yu G, Chen P, Li H, Wei D, Zhu J, Xie L, Jia H, Shi J, Li C, Yao W, Wang Y, Gao Q, Jeong L S, Lee H W, Yu J, Hu F, Mei J, Wang P, Chu Y, Qi H, Yang M, Dong Z, Sun Y, Hoffman R M, Jia L (2014). Overactivated neddylation pathway as a therapeutic target in lung cancer. J Natl Cancer Inst 106(6): dju083.
2. Zhang M, Xiang S, Joo H Y, Wang L, Williams K A, Liu W, Hu C, Tong D, Haakenson J, Wang C, Zhang S, Pavlovicz R E, Jones A, Schmidt K H, Tang J, Dong H, Shan B, Fang B, Radhakrishnan R, Glazer P M, Matthias P, Koomen J,Seto E, Bepler G, Nicosia S V, Chen J, Li C, Gu L, Li G M, Bai W, Wang H, Zhang X (2014). HDAC6 deacetylates and ubiquitinates MSH2 to maintain proper levels of MutSalpha. Mol Cell 55(1): 31-46.
3. Yu Y, Fuscoe J C, Zhao C, Guo C, Jia M, Qing T, Bannon D I, Lancashire L, Bao W, Du T, Luo H, Su Z, Jones W D, Moland C L, Branham W S, Qian F, Ning B, Li Y, Hong H, Guo L, Mei N, Shi T, Wang K Y, Wolfinger R D, Nikolsky Y, Walker S J, Duerksen-Hughes P, Mason C E, Tong W, Thierry-Mieg J, Thierry-Mieg D, Shi L, Wang C (2014). A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages. Nat Commun 5: 3230.
4. Qin L, Wu Y , Toneff M J, Li D, Liao L, Gao X, Bane F T, Tien J C, Xu Y, Feng Z, Yang Z, Xu Y, Theissen S M, Li Y, Young L, Xu J (2014). NCOA1 Directly Targets M-CSF1 Expression to Promote Breast Cancer Metastasis. Cancer Res 74(13): 3477-3488.
5. McGann J C, Oyer J A, Garg S, Yao H, Liu J, Feng X, Liao L, Yates J R, 3rd,Mandel G (2014). Polycomb- and REST-associated histone deacetylases are independent pathways toward a mature neuronal phenotype. Elife 3: e04235.
6. Xie M, Ye H, Hamri G C, Fussenegger M (2014). Antagonistic control of a dual-input mammalian gene switch by food additives. Nucleic Acids Res 42(14): e116.
7. Xu J, Li L, Yu G, Ying W, Gao Q, Zhang W, Li X, Ding C, Jiang Y, Wei D, Duan S, Lei Q, Li P, Shi T, Qian X, Qin J, Jia L (2014). Neddylation-Cullin 2-RBX1 E3 ligase axis targets tumor suppressor RhoB for degradation in liver cancer. Mol Cell Proteomics.
8. Okamoto S, Nakamura T, Cieplak P, Chan S F, Kalashnikova E, Liao L, Saleem S, Han X, Clemente A, Nutter A, Sances S, Brechtel C, Haus D, Haun F, Sanz-Blasco S, Huang X, Li H, Zaremba J D, Cui J, Gu Z, Nikzad R, Harrop A, McKercher S R, Godzik A, Yates J R, 3rd,Lipton S A (2014). S-nitrosylation-mediated redox transcriptional switch modulates neurogenesis and neuronal cell death. Cell Rep 8(1): 217-228.
9. An Y, Fu Y, Lu D, Wang Y, Bi W, Xu Z, Dong S, Zhang S, Wang C and Zhang W(2014). A TiO2-Au-polymer hybrid system for photoelectrochemical immunoassay of SirT1. J. Mater. Chem. B. 2014，2, 1644-1652.
10. Yu L, Zhang H, Caldarone B J, Eaton J B, Lukas R J, Kozikowski A P (2014). Recent developments in novel antidepressants targeting alpha4beta2-nicotinic acetylcholine receptors. J Med Chem 57(20): 8204-8223.
11. Du X, Shi H, Li J, Dong Y, Liang J, Ye J, Kong S, Zhang S, Zhong T, Yuan Z, Xu T, Zhuang Y, Zheng B, Geng J G, Tao W (2014). Mst1/Mst2 regulate development and function of regulatory T cells through modulation of Foxo1/Foxo3 stability in autoimmune disease. J Immunol 192(4): 1525-1535.
12. Kong L, Rao M, Ou J, Yin J, Lu W, Liu M, Pang X, Gao S (2014). Total synthesis and biological studies of cryptocin and derivatives of equisetin and fusarisetin A. Org Biomol Chem 12(38): 7591-7597.
13. Ye H, Fussenegger M (2014). Synthetic therapeutic gene circuits in mammalian cells. FEBS Lett 588(15): 2537-2544.
14. Qin W, Liu N, Wang L, Zhou M, Ren H, Bugnard E, Liu J L, Zhang L H, Vendome J, Hu J S, Xi X G (2014). Characterization of Biochemical Properties of Bacillus subtilis RecQ Helicase. J Bacteriol 196(24): 4216-4228.
15. Gao C, Dai F, Cui H, Peng S, He Y, Wang X, Yi Z , Qiu W (2014). Synthesis of novel heterocyclic ring-fused 18beta-glycyrrhetinic acid derivatives with antitumor and antimetastatic activity. Chem Biol Drug Des 84(2): 223-233.
16. Fu Y, Liu K, Sun Q, Lin B, Lu D, Xu Z, Hu C, Fan G, Zhang S, Wang C, Zhang W (2014). A highly sensitive immunosensor for calmodulin assay based on enhanced biocatalyzed precipitation adopting a dual-layered enzyme strategy. Biosens Bioelectron 56: 258-263.
17. Yao W, Wu J, Yu G, Wang R, Wang K, Li L, Chen P, Jiang Y, Cheng H, Lee H, Yu J, Qi H, Yu X, Wang P, Chu Y, Yang M, Hua Z, Ying H, Hoffman R, Jeong L, Jia L(2014). Disruption of the neddylation pathway with Nedd8-activating enzyme inhibitor MLN4924 targets tumor angiogenesis. Cell Death Dis. Feb 13;5:e1059.
18.Zhang Y, Shan B, Boyle M, Liu J, Liao L, Xu T, Yates JR 3rd(2014). Brain Proteome Changes Induced by Olfactory Learning in Drosophila. J. Proteome Res.13(8):3763–3770.