发表论文
Publications 2016

2016年研究成果

 

发表学术论文

 

A） 第一作者单位发表论文

 

  1. Luo J, Yang Z, Ma Y, Yue Z, Lin H, Qu G, Huang J, Dai W, Li C, Zheng C, Xu L, Chen H, Wang J, Li D, Siwko S, Penninger JM, Ning G, Xiao J, Liu M.LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption. Nature medicine 2016;22:539-46
  2. Xu J, Zhou L, Ji L, Chen F, Fortmann K, Zhang K, Liu Q, Li K, Wang W, Wang H, Xie W, Wang Q, Liu J, Zheng B, Zhang P, Huang S, Shi T, Zhang B, Dang Y, Chen J, O'Malley BW, Moses RE, Wang P, Li L, Xiao J, Hoffmann A, Li X. The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis. Nature communications 2016 Feb 22;7:10761.
  3. Zhao Q, Zhang J, Chen R, Wang L, Li B, Cheng H, Duan X, Zhu H, Wei W, Li J, Wu Q, Han JD, Yu W, Gao S, Li G, Wong J. Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals. Nature communications 2016;7:12464
  4. Wu Y, Quan Y, Liu Y, Liu K, Li H, Jiang Z, Zhang T, Lei H, Radek KA, Li D, Wang Z, Lu J, Wang W, Ji S, Xia Z, Lai Y.Hyperglycaemia inhibits REG3A expression to exacerbate TLR3-mediated skin inflammation in diabetes. Nature communications 2016;7:13393
  5. Wang J, Hu K, Guo J, Cheng F, Lv J, Jiang W, Lu W, Liu J, Pang X, Liu M.Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK. Nature communications 2016;7:11363
  6. Jin J, Liu J, Chen C, Liu Z, Jiang C, Chu H, Pan W, Wang X, Zhang L, Li B, Jiang C, Ge X, Xie X, Wang P.The deubiquitinase USP21 maintains the stemness of mouse embryonic stem cells via stabilization of Nanog. Nature communications 2016;7:13594
  7. He Y, Peng S, Wang J, Chen H, Cong X, Chen A, Hu M, Qin M, Wu H, Gao S, Wang L, Wang X, Yi Z, Liu M. Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer. Nature communications. doi: 10.1038/ncomms13122.
  8. Chen Y, Ma J, Lu W, Tian M, Thauvin M, Yuan C, Volovitch M, Wang Q, Holst J, Liu M, Vriz S, Ye S, Wang L, Li D. Heritable expansion of the genetic code in mouse and zebrafish. Cell Res. 2016 Dec 9.
  9. Zhou Z, Wang Y, Yan Y, Zhang Q, Cheng Y.Dendrimer-Templated Ultrasmall and Multifunctional Photothermal Agents for Efficient Tumor Ablation.ACS nano 2016;10:4863-72
  10. Liu C, Shao N, Wang Y, Cheng Y.Clustering Small Dendrimers into Nanoaggregates for Efficient DNA and siRNA Delivery with Minimal Toxicity. Advanced healthcare materials 2016;5:584-92
  11. Wang X, Lin Q, Lv F, Liu N, Xu Y, Liu M, Chen Y, Yi Z      LG-362B targets PML-RARalpha and blocks ATRA resistance of acute promyelocytic. Leukemia 2016;30:1465-74
  12. Guan Y, Ma Y, Li Q, Sun Z, Ma L, Wu L, Wang L, Zeng L, Shao Y, Chen Y, Ma N, Lu W, Hu K, Han H, Yu Y, Huang Y, Liu M, Li D.CRISPR/Cas9-mediated somatic correction of a novel coagulator factor IX gene mutation ameliorates hemophilia in mouse.EMBO molecular medicine 2016;8:477-88
  13. Wang C, Wang X, Dong K, Luo J, Zhang Q, Cheng Y. Injectable and responsively degradable hydrogel for personalized photothermal therapy.Biomaterials 2016;104:129-37
  14. Wang X, Zhang J, Wang Y, Wang C, Xiao J, Zhang Q, Cheng Y  Multi-responsive photothermal-chemotherapy with drug-loaded melanin-like nanoparticles for synergetic tumor ablation. Biomaterials 2016;81:114-24
  15. Wang Y, Yang J, Liu H, Wang X, Zhou Z, Huang Q, Song D, Cai X, Li L, Lin K, Xiao J, Liu P, Zhang Q, Cheng Y.Osteotropic peptide-mediated bone targeting for photothermal treatment of bone tumors. Biomaterials 2017;114:97-105
  16. Hu J, Chen Y, Li Y, Zhou Z, Cheng Y.A thermo-degradable hydrogel with light-tunable degradation and drug release      Biomaterials 2017;112:133-40
  17. Sun J, Luan Y, Xiang D, Tan X, Chen H, Deng Q, Zhang J, Chen M, Huang H, Wang W, Niu T, Li W, Peng H, Li S, Li L, Tang W, Li X, Wu D, Wang P.The 11S Proteasome Subunit PSME3 Is a Positive Feedforward Regulator of NF-kappaB and Important for Host Defense against Bacterial Pathogens.Cell reports 2016;14:737-49
  18. Zhang J, Wang Q, Wang M, Jiang M, Wang Y, Sun Y, Wang J, Xie T, Tang C, Tang N, Song H, Cui D, Chao R, Ding S, Ni B, Chen X, Wang Y.GASZ and mitofusin-mediated mitochondrial functions are crucial for spermatogenesis.EMBO reports 2016;17:220-34
  19. Wang F, Hu K, Cheng Y.Structure-activity relationship of dendrimers engineered with twenty common amino acids in gene delivery.Acta biomaterialia 2016;29:94-102
  20. Wang M, Cheng Y.Structure-activity relationships of fluorinated dendrimers in DNA and siRNA delivery.Acta biomaterialia 2016;46:204-10
  21. Hu J, Hu K, Cheng Y  .Tailoring the dendrimer core for efficient gene delivery.Acta biomaterialia 2016;35:1-11
  22. Xia X, Li Z, Liu K, Wu Y, Jiang D, Lai Y.Staphylococcal LTA-Induced miR-143 Inhibits Propionibacterium acnes-Mediated Inflammatory Response in Skin.The Journal of investigative dermatology 2016;136:621-30
  23. Wang X, Wang C, Zhang Q, Cheng Y.Near infrared light-responsive and injectable supramolecular hydrogels for on-demand drug delivery. Chemical communications 2016;52:978-81
  24. Lv Y, Meng B, Dong H, Jing T, Wu N, Yang Y, Huang L, Moses RE, O'Malley BW, Mei B, Li X. Upregulation of GSK3beta Contributes to Brain Disorders in Elderly REGgamma-knockout Mice.Neuropsychopharmacology:official publication of the American College of Neuropsychopharmacology 2016;41:1340-9
  25. Ma X, Pan X, Wei Y, Tan B, Yang L, Ren H, Qian M, Du B.Chemotherapy-induced uridine diphosphate release promotes breast cancer metastasis through P2Y6 activation       Oncotarget 2016;7:29036-50
  26. Guo J, Lv J, Chang S, Chen Z, Lu W, Xu C, Liu M, Pang X.Inhibiting cytoplasmic accumulation of HuR synergizes genotoxic agents in urothelial carcinoma of the bladder.Oncotarget  2016 Jun 9  doi: 10 18632/oncotarget 9932  [Epub ahead of print]
  27. Shi JP, Wang SY, Chen LL, Zhang XY, Zhao YH, Du B, Jiang WZ, Qian M, Ren H.P2Y6 contributes to ovalbumin-induced allergic asthma by enhancing mast cell function in mice.Oncotarget 2016
  28. Fang L, Zhang J, Zhang H, Yang X, Jin X, Zhang L, Skalnik DG, Jin Y, Zhang Y, Huang X, Li J, Wong J.H3K4 Methyltransferase Set1a Is A Key Oct4 Coactivator Essential for Generation of Oct4 Positive Inner Cell Mass.Stem cells 2016;34:565-80
  29. Yuan Y, Yu X, Zhang Q, Chang M, Li L, Yang T, Chen Y, Pan H, Zhang S, Li L, Xu J.Sensitive Detection of Polycyclic Aromatic Molecules: Surface Enhanced Raman Scattering via pi-pi Stacking. Analytical chemistry 2016;88:4328-35
  30. Xu L, Luo J, Jin R, Yue Z, Sun P, Yang Z, Yang X, Wan W, Zhang J, Li S, Liu M, Xiao J.       Bortezomib Inhibits Giant Cell Tumor of Bone through Induction of Cell Apoptosis and Inhibition of Osteoclast Recruitment, Giant Cell Formation, and Bone Resorption.   Molecular cancer therapeutics 2016;15:854-65
  31. Zhou W, Tang W, Sun Z, Li Y, Dong Y, Pei H, Peng Y, Wang J, Shao T, Jiang Z, Yi Z, Chen Y. Discovery and Optimization of N-Substituted 2-(4-pyridinyl)thiazole carboxamides against Tumor Growth through Regulating Angiogenesis Signaling Pathways.Scientific reports 2016;6:33434
  32. You P, Hu H, Chen Y, Zhao Y, Yang Y, Wang T, Xing R, Shao Y, Zhang W, Li D, Chen H, Liu M. Effects of Melanocortin 3 and 4 Receptor Deficiency on Energy Homeostasis in Rats.Scientific reports 2016;6:34938
  33. Wang X, Wang H, Wang Y, Yu X, Zhang S, Zhang Q, Cheng Y.A Facile Strategy to Prepare Dendrimer-stabilized Gold Nanorods with Sub-10-nm Size for Efficient Photothermal Cancer Therapy.Scientific reports 2016;6:22764
  34. Liu H, Chang H, Lv J, Jiang C, Li Z, Wang F, Wang H, Wang M, Liu C, Wang X, Shao N, He B, Shen W, Zhang Q, Cheng Y.Screening of efficient siRNA carriers in a library of surface-engineered dendrimers.Scientific reports 2016;6:25069
  35. Shi J, Zhang X, Wang S, Wang J, Du B, Wang Z, Liu M, Jiang W, Qian M, Ren H   Gpr97 is dispensable for metabolic syndrome but is involved in macrophage inflammation in high-fat diet-induced obesity in mice.Scientific reports 2016;6:24649
  36. Chen A, Zhou X, Tang S, Liu M, Wang X.Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach.Scientific reports 2016;6:28482
  37. Chen J, Guo J, Chen Z, Wang J, Liu M, Pang X.Linifanib (ABT-869) Potentiates the Efficacy of Chemotherapeutic Agents through the Suppression of Receptor Tyrosine Kinase-Mediated AKT/mTOR Signaling Pathways in Gastric Cancer.Scientific reports 2016;6:29382
  38. Zhang X, Qin J, Zou J, Lv Z, Tan B, Shi J, Zhao Y, Ren H, Liu M, Qian M, Du B.Extracellular ADP facilitates monocyte recruitment in bacterial infection via ERK signaling.Cellular & molecular immunology 2016
  39. Wang X, Tang Y, Lu J, Shao Y, Qin X, Li Y, Wang L, Li D, Liu M.Characterization of novel cytochrome P450 2E1 knockout rat model generated by CRISPR/Cas9.Biochemical pharmacology 2016;105:80-90
  40. Qin J, Zhang G, Zhang X, Tan B, Lv Z, Liu M, Ren H, Qian M, Du B.TLR-Activated Gap Junction Channels Protect Mice against Bacterial Infection through Extracellular UDP Release.Journal of immunology 2016;196:1790-8
  41. Zhang Q, Zhou Z, Wang Y, Cheng Y.How can we use dendrimer-templated ultrasmall and multifunctional nanoparticles in photothermal cancer therapy? Nanomedicine 2016;11:3181-3    
  42. Qin X, Liu M, Wang X.New insights into the androgen biotransformation in prostate cancer: A regulatory network among androgen, androgen receptors and UGTs.Pharmacological research 2016;106:114-22
  43. Wang F, Deng L, Hu J, Cheng Y.Being Two Is Better than Being One: A Facile Strategy to Fabricate Multicomponent Nanoparticles for Efficient Gene Delivery.Bioconjugate chemistry 2016;27:638-46
  44. Wang M, Cheng Y.Temperature-Responsive Gene Silencing by a Smart Polymer      Bioconjugate chemistry 2016;27:495-9
  45. Zhao LH, Yin Y, Yang D, Liu B, Hou L, Wang X, Pal K, Jiang Y, Feng Y, Cai X, Dai A, Liu M, Wang MW, Melcher K, Xu HE.Differential Requirement of the Extracellular Domain in Activation of Class B G Protein-coupled Receptors.The Journal of biological chemistry 2016;291:15119-30
  46. Ding G, Chen P, Zhang H, Huang X, Zang Y, Li J, Li J, Wong J.Regulation of Ubiquitin-like with Plant Homeodomain and RING Finger Domain 1 (UHRF1) Protein Stability by Heat Shock Protein 90 Chaperone Machinery.The Journal of biological chemistry 2016;291:20125-35
  47. Wu Y, Wang X, Chang S, Lu W, Liu M, Pang X.beta-Lapachone Induces NAD(P)H:Quinone Oxidoreductase-1- and Oxidative Stress-Dependent Heat Shock Protein 90 Cleavage and Inhibits Tumor Growth and Angiogenesis.The Journal of pharmacology and experimental therapeutics 2016;357:466-75
  48. Ren X, Shi Y, Zhao D, Xu M, Li X, Dang Y, Ye X.Naringin protects ultraviolet B-induced skin damage by regulating p38 MAPK signal pathway.Journal of dermatological science 2016;82:106-14
  49. Zhao J, Zeng Z, Sun J, Zhang Y, Li D, Zhang X, Liu M, Wang X.A Novel Model of P-Glycoprotein Inhibitor Screening Using Human Small Intestinal Organoids.Basic & clinical pharmacology & toxicology 2016
  50. Zhang Y, Zeng Z, Zhao J, Li D, Liu M, Wang X.Measurement of Rhodamine 123 in Three-Dimensional Organoids: A Novel Model for P-Glycoprotein Inhibitor Screening.Basic & clinical pharmacology & toxicology 2016;119:349-52
  51. Ye X, Qian Y, Wang Q, Yuan W, Mo X, Li Y, Jiang Z, Xu W, Deng Y, Wan Y, Fan X, Wu X, Wang Y.SMYD1, an SRF-Interacting Partner, Is Involved in Angiogenesis.PloS one 2016;11:e0146468
  52. Huang Q, Wei H, Wu Z, Li L, Yao L, Sun Z, Li L, Lin Z, Xu W, Han S, Cao W, Xu Y, Song D, Yang X, Xiao J.Preferentially Expressed Antigen of Melanoma Prevents Lung Cancer Metastasis.PloS one 2016;11:e0149640
  53. Yang F, Peng S, Li Y, Su L, Peng Y, Wu J, Chen H, Liu M, Yi Z, Chen Y.A hybrid of thiazolidinone with the hydroxamate scaffold for developing novel histone deacetylase inhibitors with antitumor activities.Organic & biomolecular chemistry 2016;14:1727-35
  54. Wang H, Huang Q, Chang H, Xiao J, Cheng Y.Stimuli-responsive dendrimers in drug delivery. Biomaterials science 2016;4:375-90
  55. Du Y, Shi T.Ligand cluster-based protein network and ePlatton, a multi-target ligand finder.Journal of cheminformatics 2016;8:23
  56. Pang X, Liu M.A combination therapy for KRAS-mutant lung cancer by targeting synthetic lethal partners of mutant KRAS.Chinese journal of cancer 2016;35:92
  57. Zhang X, Qin J, Zhao Y, Shi J, Lan R, Gan Y, Ren H, Zhu B, Qian M, Du B.Long-term ketogenic diet contributes to glycemic control but promotes lipid accumulation and hepatic steatosis in type 2 diabetic mice. Nutrition research 2016;36:349-58
  58. Lei H, Wang Y, Zhang T, Chang L, Wu Y, Lai Y.TLR3 activation induces S100A7 to regulate keratinocyte differentiation after skin injury.Science China Life sciences 2016
  59. Chen G, Chen J, Yang J, Chen L, Qu X, Shi C, Ning B, Shi L, Tong W, Zhao Y, Zhang M, Shi T.Significant variations in alternative splicing patterns and expression profiles between human-mouse orthologs in early embryos.Science China Life sciences 2016
  60. Chen Y, Lu W, Gao N, Long Y, Shao Y, Liu M, Chen H, Ye S, Ma X, Liu M, Li D.Generation of obese rat model by transcription activator-like effector nucleases targeting the leptin receptor gene.Science China Life sciences 2016
  61. Gong X, Chao R, Wang P, Huang X, Zhang J, Zhu X, Zhang Y, Yang X, Hou C, Ji X, Shi T, Wang Y.Interplay of transcription factors and microRNAs during embryonic hematopoiesis.Science China Life sciences 2016
  62. Guo J, Yu W, Su H, Pang X.Genomic landscape of gastric cancer: molecular classification and potential targets. Science China Life sciences 2016
  63. Chen Y, Lv J, Li K, Xu J, Li M, Zhang W, Pang X  .Sporoderm-Broken Spores of Ganoderma lucidum Inhibit the Growth of Lung Cancer: Involvement of the Akt/mTOR Signaling Pathway. Nutrition and cancer 2016;68:1151-60
  64. Lv J, Wang J, Chang S, Liu M, Pang X.The greedy nature of mutant RAS: a boon for drug discovery targeting cancer metabolism? Acta biochimica et biophysica Sinica 2016;48:17-26
  65. Tian X, Xin M, Luo J, Liu M, Jiang Z.Identification of Genes Involved in Breast Cancer Metastasis by Integrating Protein-Protein Interaction Information with Expression. Data Journal of computational biology : a journal of computational molecular cell biology 2016
  66. Pang X, Liu M.Defeat mutant KRAS with synthetic lethality.Small GTPases 2016:1-8
  67. Jia Y, Li P, Fang L, Zhu H, Xu L, Cheng H, Zhang J, Li F, Feng Y, Li Y, Li J, Wang R, Du JX, Li J, Chen T, Ji H, Han J, Yu W, Wu Q, Wong J.Negative regulation of DNMT3A de novo DNA methylation by frequently overexpressed UHRF family proteins as a mechanism for widespread DNA hypomethylation in cancer.Cell discovery 2016;2:16007
  68. Dong D, Lei M, Hua P, Pan YH, Mu S, Zheng G, Pang E, Lin K, Zhang S.The genomes of two bat species with long constant frequency echolocation calls.Molecular biology and evolution 2016

 

B）合作发表论文

  1. Fang J, Cheng J, Wang J, Zhang Q, Liu M, Gong R, Wang P, Zhang X, Feng Y, Lan W, Gong Z, Tang C, Wong J, Yang H, Cao C, Xu Y.Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition.Nature communications 2016;7:11197
  2. Sun L, Fan G, Shan P, Qiu X, Dong S, Liao L, Yu C, Wang T, Gu X, Li Q, Song X, Cao L, Li X, Cui Y, Zhang S, Wang C.Regulation of energy homeostasis by the ubiquitin-independent REGgamma proteasome.Nature communications 2016;7:12497
  3. Bai P, Ye H, Xie M, Saxena P, Zulewski H, Charpin-El Hamri G, Djonov V, Fussenegger M.A synthetic biology-based device prevents liver injury in mice.Journal of hepatology 2016;65:84-94
  4. Xu DQ, Wang Z, Wang CY, Zhang DY, Wan HD, Zhao ZL, Gu J, Zhang YX, Li ZG, Man KY, Pan Y, Wang ZF, Ke ZJ, Liu ZX, Liao LJ, Chen Y.PAQR3 controls autophagy by integrating AMPK signaling to enhance ATG14L-associated PI3K activity.The EMBO journal 2016;35:496-514
  5. Ma H, Luo J, Sun Z, Xia L, Shi M, Liu M, Chang J, Wu C.3D printing of biomaterials with mussel-inspired nanostructures for tumor therapy and tissue regeneration.Biomaterials 2016;111:138-48
  6.  Rodriguez M, Siwko S, Zeng L, Li J, Yi Z, Liu M.Prostate-specific.G-protein-coupled receptor collaborates with loss of PTEN to promote prostate cancer progression. Oncogene 2016;35:1153-62
  7.  Wang W, Liao P, Shen M, Chen T, Chen Y, Li Y, Lin X, Ge X, Wang P.SCP1 regulates c-Myc stability and functions through dephosphorylating c-Myc Ser62. Oncogene 2016;35:491-500
  8.  Li J, Zhai D, Lv F, Yu Q, Ma H, Yin J, Yi Z, Liu M, Chang J, Wu C.Preparation of copper-containing bioactive glass/eggshell membrane nanocomposites for improving angiogenesis, antibacterial activity and wound healing   .Acta biomaterialia 2016;36:254-66
  9. Chen Y, Liu X, Zhang Y, Wang H, Ying H, Liu M, Li D, Lui KO, Ding Q.A Self-restricted CRISPR System to Reduce Off-target Effects. Molecular therapy : the journal of the American Society of Gene Therapy 2016;24:1508-10
  10. Huang Q, Li L, Li L, Chen H, Dang Y, Zhang J, Shao N, Chang H, Zhou Z, Liu C, He B, Wei H, Xiao J.MDM2 knockdown mediated by a triazine-modified dendrimer in the treatment of non-small cell lung cancer.Oncotarget  2016;7:44013-22
  11.  Liu XM, Zhang YP, Ji SY, Li BT, Tian X, Li D, Tong C, Fan HY Mitoguardin-1 and -2 promote maturation and the developmental potential of mouse oocytes by maintaining mitochondrial dynamics and functions.Oncotarget 2016;7:1155-67
  12. Qian J, Hu Y, Zhao L, Xia J, Li C, Shi L, Xu F.Protective Role of Adipose-Derived Stem Cells in Staphylococcus aureus-Induced Lung Injury is Mediated by RegIIIgamma Secretion.Stem cells 2016;34:1947-56
  13.  Wu Z, Lu W, Wu D, Luo A, Bian H, Li J, Li W, Liu G, Huang J, Cheng F, Tang Y.In silico prediction of chemical mechanism of action via an improved network-based inference method. British journal of pharmacology 2016
  14.  Xiao Q, Dong N, Yao X, Wu D, Lu Y, Mao F, Zhu J, Li J, Huang J, Chen A, Huang L, Wang X, Yang G, He G, Xu Y, Lu W   .Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H    .Scientific reports 2016;6:25298
  15. Zhang L, Shao Y, Li L, Tian F, Cen J, Chen X, Hu D, Zhou Y, Xie W, Zheng Y, Ji Y, Liu M, Li D, Hui L.Efficient liver repopulation of transplanted hepatocyte prevents cirrhosis in a rat model of hereditary tyrosinemia type I .Scientific reports 2016;6:31460
  16. Zhang L, Wong J, Vanacker JM.The estrogen-related receptors (ERRs): potential targets against bone loss.Cellular and molecular life sciences : CMLS 2016;73:3781-7
  17.  Huang Y, Chen B, Ye M, Liang P, Zhangfang Y, Huang J, Liu M, Songyang Z, Ma W.Ccndbp1 is a new positive regulator of skeletal myogenesis.Journal of cell science 2016;129:2767-77
  18. Li L, Huang Q, Wang C, Wang X, Xiao J, Zhang Q, Cheng Y.Bone and metal targeted polymeric nanoparticles (US20150125391 A1): a patent evaluation.Expert opinion on therapeutic patents 2016;26:987-91
  19.  Cui HW, Peng S, Gu XZ, Chen H, He Y, Gao W, Lv F, Wang JH, Wang Y, Xie J, Liu MY, Yi Z, Qiu WW.Synthesis and biological evaluation of D-ring fused 1,2,3-thiadiazole dehydroepiandrosterone derivatives as antitumor agents.European journal of medicinal chemistry 2016;111:126-37
  20.  Ko SG, Yin CS, Du B, Kim KH.Herbal Medicines for Inflammatory Diseases 2016.Mediators of inflammation 2016;2016:8270323
  21.  Lang L, Dong N, Wu D, Yao X, Lu W, Zhang C, Ouyang P, Zhu J, Tang Y, Wang W, Li J, Huang J.2-Arylbenzo[b]furan derivatives as potent human lipoxygenase inhibitors.Journal of enzyme inhibition and medicinal chemistry 2016:1-8
  22. Li Z, Su H, Yu W, Li X, Cheng H, Liu M, Pang X, Zou X.Design, synthesis and anticancer activities of novel otobain derivatives.Organic & biomolecular chemistry 2016;14:277-87
  23. Mao SW, Chen H, Yu LF, Lv F, Xing YJ, Liu T, Xie J, Tang J, Yi Z, Yang F.Novel 3,4-seco bile acid diamides as selective anticancer proliferation and migration agents .European journal of medicinal chemistry 2016;122:574-83
  24. Wang YY, He Y, Yang LF, Peng SH, He XL, Wang JH, Lv F, Hao Y, Liu MY, Yi Z, Qiu WW. Synthesis of novel diterpenoid analogs with in-vivo antitumor activity. European journal of medicinal chemistry 2016;120:13-25
  25.  Yao X, Wu D, Dong N, Ouyang P, Pu J, Hu Q, Wang J, Lu W, Huang J.Moracin C, A Phenolic Compound Isolated from Artocarpus heterophyllus, Suppresses Lipopolysaccharide-Activated Inflammatory Responses in Murine Raw264.7.Macrophages International journal of molecular sciences 2016;17
  26. Chen G, Shi T, Shi L.Characterizing and annotating the genome using RNA-seq data.Science China Life sciences 2016
  27. Chen G, Yang J, Chen J, Song Y, Cao R, Shi T, Shi L.Identifying and annotating human bifunctional RNAs reveals their versatile functions. Science China Life sciences 2016;59:981-92
  28.  Pan H, Hu Q, Wang J, Liu Z, Wu D, Lu W, Huang J.Myricetin is a novel inhibitor of human inosine 5'-monophosphate dehydrogenase with anti-leukemia activity. Biochemical and biophysical research communications 2016;477:915-22
  29. Sun Z, Wu Z, Zhang F, Guo Q, Li L, Li K, Chen H, Zhao J, Song D, Huang Q, Li L, Xiao J.PRAME is critical for breast cancer growth and metastasis.Gene 2016;594:160-4


2017-10-30

上海市调控生物学重点实验室    上海市东川路500号华东师范大学生命科学学院生命医学研究所    邮编 200241   联系人：韩姬    沪ICP备05003394

Email:jhan@bio.ecnu.edu.cn    电话：021-54344030    技术支持：ECNU信息化办公室